Epidemiology and biology of the metabolic syndrome in adult survivors of childhood cancer.

Epidemiology and biology of the metabolic syndrome in adult survivors of childhood cancer. - Metabolic syndrome in childhood cancer survivors.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35166

Enrollment

1200

Registered

2009-04-08

Start date

2009-10-05

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiovascular diseases

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patient: - history of childhood cancer - treated in ErasmusMC-Sophia - at least 18 years old - minimum of 5 years after cessation of therapy Control: - preferrably brother or sister of the patient, if not available; - friend or neighbour of survivor of same sex and approximately same age, within a range of 5 years.

Exclusion criteria

Exclusion criteria: Patient: - when partly treated in other country Controls: - when they also have a history of childhood cancer

Design outcomes

Primary

Measure	Time frame
- blood pressure - body composition - (abdominal) obesity - glucose metabolism - lipidspectrum	—

Secondary

Measure	Time frame
-polymorphisms -other parameters associated with the metabolic syndrome: biomarkers for endothelial function pro-inflammatory markers pro-thrombotic factors biomarkers for adiposity *urine-analysis - results of fitness test	—

Countries

Netherlands

Outcome results