Diagnostics using perfusion CT imaging to determine the extent of bone marrow involvement of the mandible by squamous cell carcinoma - a pilot study

Diagnostics using perfusion CT imaging to determine the extent of bone marrow involvement of the mandible by squamous cell carcinoma - a pilot study - Bone marrow involvement of the mandible using perfusion CT imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35141

Enrollment

Registered

2010-04-20

Start date

2010-08-03

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral cancer oral cavity carcinoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients, 18 year of age or older, with a squamous cell carcinoma of the oral cavity or oropharynx, fixed to the mandible. Conventional X-ray imaging shows cortical or bonemarrow mandibular involvement.

Exclusion criteria

Exclusion criteria: Prior surgry in the head and neck region or cervicofacial radiotherapy. Mandibular osteomyelitis, recent tooth removal(s). Allergy for contrast agent. Severe kidney diseases.

Design outcomes

Primary

Measure	Time frame
Determine the extension of bone marrow involvement of the mandible by SCC.	—

Secondary

Measure	Time frame
Perfusion CT imaging can prevent unnecessary resection of the mandible.	—

Countries

Netherlands

Outcome results