intensive care patienten die met bloedtransfusie behandeld worden anemia non-sepsis sepsis
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1.Intensive care patients receiving blood transfusion therapy 2.Approval from the physician that will be treating the patients 3.Informed consent from each participating patient 4.Patients older than 18 years old 5.Transfusion of blood from storage age less than 1 week and more than 3 weeks 6.Patients in whom the doses of vasopressor/inotropic and sedative/analgesic agents are kept constant
Exclusion criteria
Exclusion criteria: 1. Patients that did not sign an informed consent 2. Patients younger than 18 years 3. Indication for irradiated and/or washed blood products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Noninvasive measurements: Sidestream Dark-Field (SDF) Imaging-microcirculation quantification: FCD (functional capillary density), MFI (microvascular flow index) Fibre spectrophotometry and laser Doppler flowmetry (O2C): Microcirculatory hemoglobin saturation and flow in superficial layers Near-infrared spectroscopy (NIRS): Microcirculatory hemoglobin saturation and flow in deep layers Invasive measurements: Blood sample | — |
Secondary
| Measure | Time frame |
|---|---|
| N.v.t. | — |
Countries
Netherlands
Outcome results
None listed