Effects of a combined functional walking and strength trainig on the stability of walking and the rate of bone turnover in inactive, but healthy elderly

Effects of a combined functional walking and strength trainig on the stability of walking and the rate of bone turnover in inactive, but healthy elderly - stability of walking and bone turnover after training in elderly

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON35091

Enrollment

Registered

2010-05-17

Start date

2010-05-25

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

veroudering aging senescent

Interventions

During 16 weeks the trainings group (20 participants) will perform a combined functional gait and strength training. Each training will last 60 minutes and will take place in the VU sports center tw

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - man/woman between the age of 65-75 years - not meet the requirements of the Nederlandse Norm Gezond Bewegen (NNGB) --> less than 5 x 30 min. per week active - no active participation in sports for the last year

Exclusion criteria

Exclusion criteria: - Chronic (progressive) disorder which affects the sensory or motor function (i.e. CVA, Parkinson, severe arthritis) - cardiac problems (heart failure, aneurysm, heart rhythm complaints, claudicatio intermittens) over the past 10 years - thrombosis or emboli over the past 10 years - Instable metabolic disorder (i.e. diabetes) - bone fracture over the past 2 years - Vertebra collapse - Walking with walking aid - Cognitive limitations;The in- and exclusion criteria will be asked during a conversation on the phone. In addition, the Mini-Mental State Examination will be taken to get an impression about their cognitive abilities. People scoring *27 will be excluded from the study.

Design outcomes

Primary

Measure	Time frame
The main study parameters are: - to measure the stability of walking: the Lyapunov exponent - to measure the rate of bone turnover: CTx (C-terminal cross-linking-telopeptide of type 1 collagen) which is a biochemical marker of bone resorption and osteocalcin and P1NP (procollagen typ-1 N propeptide) as markers of bone formation will be measured.	—

Secondary

Measure	Time frame
Secondary study parameters are: for gait measurements: - electromyography (EMG) - oxygen consumption for muscle function: - cm (horizontal jump height) - force - EMG - serum concentration of the systemic growth factors IGF-1 and myostatin for bone quality - in order to measure the quality of the heel bone broad band ultrasound attenuation (BUA) and speed of sound (SOS) will be measured, using quantitative ultrasound for daily actitivies - LASA physical activity questionnaire (LAPAQ)	—

Measure

Time frame

Secondary study parameters are: for gait measurements: - electromyography (EMG) - oxygen consumption for muscle function: - cm (horizontal jump height) - force - EMG - serum concentration of the systemic growth factors IGF-1 and myostatin for bone quality - in order to measure the quality of the heel bone broad band ultrasound attenuation (BUA) and speed of sound (SOS) will be measured, using quantitative ultrasound for daily actitivies - LASA physical activity questionnaire (LAPAQ)

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)