Pre-operative CT scan in breast conserving therapy for more accurate radiation boost volume delineation.

Pre-operative CT scan in breast conserving therapy for more accurate radiation boost volume delineation. - PRESCRIBE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35059

Enrollment

Registered

2010-09-20

Start date

2010-06-15

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breastcancer cancer of the breast

Interventions

Pre operative CT scan will be performed with the following conditions: * CT scan (GE, The LightSpeed® RT16) * 2.5 mm slides * Radiotherapy position, indicating supine on a C-Qual breast board (CIVCO

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: cT1-3N0 breastcancer, calculated creatinine clearance > 60 ml/liter (Cockroft) , informed consent

Exclusion criteria

Exclusion criteria: post operative mastitis or wounddefect, contra indication for iv.contrast, neo adjuvant systemic treatment

Design outcomes

Primary

Measure	Time frame
Primary: Difference in position of the pre-operative tumour on CT and postoperative reconstruction of the tumour-location using current standard information: GTVsim en GTVpre Difference in position of the radiotherapy boost by using the pre- operative CT scan, compared with the postoperative simulation CT scan: CTVsim en CTVpre Difference in volume of CTVsim en CTVpre	—

Secondary

Measure	Time frame
Secondary: Change of contour of the breast after surgery Decreasing the interobserver delineation on CTVpre compared to CTVsim between the 4 observers	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)