niet van toepassing not applicable
Conditions
Interventions
All participants will receive two different theta-burst stimulations of 600
pulses and one repetitive TMS (5Hz.) of 200 pulses at 80% of active motor
threshold on three different sessions:
1. Contin
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy, right-handed males aged 18-35 years. All subjects will have normal or corrected-to-normal vision.
Exclusion criteria
Exclusion criteria: Contra-indications for TMS and fMRI: drug abuse, head trauma, neurological or psychiatric illness, pregnancy, heart disease, claustrophobia, cardiac pacemakers, metal objects in the body, medication pumps, tricyclic antidepressants, neuroleptics and a family history of neurological illness, psychiatric illness or epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reaction times and error rates on the approach-avoidance task will be used to test whether the congruency effect in the cTBS condition applied over the vlPFC is larger than in the other TMS conditions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Aarterial spin labelling during task performance is used to investigate the effects of the different TMS conditions on cerebral blood flow. Moreover, hormonal levels of cortisol and testosterone are measured in order to control for differences in performance on the approach-avoidance-task between subjects. | — |
Countries
Netherlands
Outcome results
None listed