Role of diaphragm fatigue in weaning from mechanical ventilation

Role of diaphragm fatigue in weaning from mechanical ventilation - Diaphragm fatigue in weaning

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON35029

Enrollment

Registered

2010-04-27

Start date

2010-10-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fatigue diaphragm fatigue respiratory muscles

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - age 18 year or older - mechanical ventilation for at least 3 days - the primary physician judges the patient to be ready to be weaned from the ventilator - informed consent

Exclusion criteria

Exclusion criteria: - pre-existent muscle disease (congenital or acquired) or diseases / disorders know to be associated with myopathy including diabetes and auto-immune diseases. - upper airway / esophageal pathology (i.e. recent surgery, esophageal varices, diaphragmatic hernia) - recent (

Design outcomes

Primary

Measure	Time frame
Main study parameters are the diaphragm efficiency (Edi/Pdi) and tension time index.	—

Secondary

Measure	Time frame
Not applicable.	—

Countries

Netherlands

Outcome results