STUDY TO INVESTIGATE THE EFFECTS OF LEVOCETIRIZINE AND DIPHENHYDRAMINE ON COGNITIVE AND PSYCHOMOTOR FUNCTIONING DURING SIMULATED DIVING AT 2 BAR AND 4 BAR IN PROFESSIONAL NAVY DIVERS

STUDY TO INVESTIGATE THE EFFECTS OF LEVOCETIRIZINE AND DIPHENHYDRAMINE ON COGNITIVE AND PSYCHOMOTOR FUNCTIONING DURING SIMULATED DIVING AT 2 BAR AND 4 BAR IN PROFESSIONAL NAVY DIVERS - Levocetirizine and Diving

Status

Unknown

Phases

Phase 4

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON35024

Enrollment

Registered

2010-04-09

Start date

2010-04-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergische rhinitis Allergic rhinitis

Interventions

Each subject performs 3 test days: levocetirizine (5 mg), diphenhydramine (50 mg) and placebo.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Man He is aged between 18 and 55 years old BMI between 18 and 30 Written informed consent Normal static binocular acuity, corrected or uncorrected Normal hearing Possession of a valid divers certificate and medical fit for diving Be considered as reliable and mentally capable of adhering to the protocol.

Exclusion criteria

Exclusion criteria: Current drug use (questionnaire at the start of the test day) Use of psychoactive medication Prior enrolment in the same study Physical or mental illness Excessive alcohol use (>21 alcoholic drinks per week) Intake of caffeine-containing beverages over 5 glasses per day Smoker

Design outcomes

Primary

Measure	Time frame
Reaction time.	—

Secondary

Measure	Time frame
The percentage of errors on the tests.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)