littekens cicatrix scar
Conditions
Interventions
A test region (at least 2x2cm but smaller than 5x5cm) will be treated three
times every four weeks with the UltraPulse Encore 10600nm Deep FX fractional
laser. First, the skin will be cleaned with c
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Atrophic or hypertrophic scars allowing for demarcation of two similar test regions of at least 2x2 cm; Age at least 18 years; Subject is willing and able to give written informed consent; Interval between injury and start of study at least one year.
Exclusion criteria
Exclusion criteria: Suspected allergy to lidocaine; Use of isotretinoin in the past 6 months; Subjects not competent to understand what is involved; Skin type V and VI Pregnancy; Concomitant skin disease at the site of treatment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blinded Physicians Global Assessment is the main outcome variable. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary variables are Patient*s Global Assessment, blinded clinical assessment of the scar on a scale from 0-3 (erythema, pigmentation, texture, hypertrophy, atrophy, pliability), Patient and Observer Scar Scale (POSAS), objective colour measurements by reflectance spectroscopy (LAB) and chromameter (erythema index, melanin index). | — |
Countries
Netherlands
Outcome results
None listed