Combined Dynamic MR enterography and colonography in pediatric patients with suspected IBD

Combined Dynamic MR enterography and colonography in pediatric patients with suspected IBD - DCE-MRI in pediatric patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34999

Enrollment

Registered

2010-06-21

Start date

2010-04-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease inflammatory bowel disease

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Clinically suspected inflammatory bowel disease Scheduled to undergo endoscopy Scheduled to undergo MRI Written Informed patients (>12 years of age) and parental consent

Exclusion criteria

Exclusion criteria: Age 18 years General contraindications for MRI (such as pregnancy, claustrophobia, renal insufficiency) or endoscopy Lack of written informed consent Inability to perform a 20 second breath hold Inability to drink 800 ml of the oral contrast agent (Sorbitol).

Design outcomes

Secondary

Measure	Time frame
The secondary study parameters will be the comparison of DCE-MRI with histopathological biopsies and Pedriatric Crohn*s Disease Activity Index en Pediatric Ulcerative Colitis Activity Index scores for grading disease activity in IBD patients.	—

Primary

Measure	Time frame
The main study parameter will be the accuracy of diagnosing CD or UC with dynamic contrast enhanced MR enterography and colonography as compared to upper and lower tract endoscopy and abdominal ultrasound.	—

Countries

Netherlands

Outcome results