cognitive dysfunction memory and attention
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients over 65 years of age admitted to the Department of Surgery of the University Center Groningen for the surgical or combined cancer treatment (surgery / radiation /chemotherapy / hormonal therapy) of a solid tumor will be included in this study. This will include patients undergoing surgery for a malignancy of the breast, thyroid, soft tissue, hepatobilliairy tract, colorectal tumors, and skin tumors• surgery is scheduled more than 24 hours after inclusion in the study as we feel this is the time necessary to obtain test results and plan the intraoperative recording of data • surgery under general, local or regional anesthesia. • written informed consent given according to local regulations
Exclusion criteria
Exclusion criteria: • any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule.;• patient unable to comply with the outcome questionnaires
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of POCD defined by a postoperative change in cognitive function measured by the Ruff Figural Fluency (RFFT) score and Trailmaking test (TMT) score in comparison to the preoperatieve score. Secondary outcome measures are | — |
Secondary
| Measure | Time frame |
|---|---|
| memory (measured by the 15 words test) and daily functioning and quality of life measured by the instruments in the "minimale dataset (MDS)". These tests will be performed preoperatively and at discharge (or a maximum of 2 weeks postoperatively) and 3 months postoperatively. | — |
Countries
Netherlands
Outcome results
None listed