The Gilles de la Tourette follow-up study: a study on the long term development of GTS.

The Gilles de la Tourette follow-up study: a study on the long term development of GTS. - The Tourette follow-up study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34954

Enrollment

310

Registered

2010-08-26

Start date

2010-10-18

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bewegingsstoornissen tics Tourette syndrome

Interventions

None listed

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: Persons with GTS and their partners.

Exclusion criteria

Exclusion criteria: Persons on whom baseline measurements are incomplete or un available.

Design outcomes

Primary

Measure	Time frame
Primary outcome variables will be (change in) tic diagnosis and tic severity using the Yale Global tic severity scale (YGTSS).	—

Secondary

Measure	Time frame
Secondary outcome variables are: (change in) OCD diagnosis and OC symptom severity (measured with the YBOCS), (change in) ADHD diagnosis and severity (measured with the CAARS), and (change in) Quality of Life measured with the QOL. Information obtained through the partners will be used in the analyses to establish pschosoial functionning in the patients. The following variables are used to enter in the models as predictors of outcome: baseline tics/ tic severity, baseline OC symptom severity, baseline severity of ADHD, age at onset, illness duration, sex, family history, number and severity of life events, and psychosocial status at baseline. Neuropsychological parameters that are used in association with tic severity, and severity of comorbid OCD/ ADHD are: Stroop color-word test and Stroop interference control (cognitive inhibition), Go-no-Go task (motor inhibition), ID/ED set shifting task.	—

Measure

Time frame

Secondary outcome variables are: (change in) OCD diagnosis and OC symptom severity (measured with the YBOCS), (change in) ADHD diagnosis and severity (measured with the CAARS), and (change in) Quality of Life measured with the QOL. Information obtained through the partners will be used in the analyses to establish pschosoial functionning in the patients. The following variables are used to enter in the models as predictors of outcome: baseline tics/ tic severity, baseline OC symptom severity, baseline severity of ADHD, age at onset, illness duration, sex, family history, number and severity of life events, and psychosocial status at baseline. Neuropsychological parameters that are used in association with tic severity, and severity of comorbid OCD/ ADHD are: Stroop color-word test and Stroop interference control (cognitive inhibition), Go-no-Go task (motor inhibition), ID/ED set shifting task.

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Countries

Netherlands

Outcome results