Novel approaches to investigating Executive Functions in Depression: the effect of mindfulness

Novel approaches to investigating Executive Functions in Depression: the effect of mindfulness - Executive Functions in depression

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON34950

Enrollment

Registered

2011-02-17

Start date

2011-02-18

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recurrent depression recurrent depressive disorder

Interventions

The mindfulness based cognitive therapy (MBCT) course consists of eight weekly sessions of 2.5 hours and a silent day. The groups consist of 8 to 15 people. During the course, patients exercise with

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: >Current major depression or depression in remission according to Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I; First, Spitzer, Gibbon, & Williams, 1995)

Exclusion criteria

Exclusion criteria: •Current Psychosis •Substance addiction in the last 6 months •Deafness •Blindness •Neurological disorder •Sensorimotor handicaps •Inadequate command of the Dutch language

Design outcomes

Primary

Measure	Time frame
For the cross-sectional comparison of depressed patients, patients in remission, and healthy subjects, we will use the following outcomes: - Response times on the Stroop test with emotional facial expressions. - Number of items correctly remembered emotional faces or scenes. - Direct measurement of attention for emotional faces through the eye-tracking test. To compare the effect of a mindfulness course vs. a waiting list control group, the following parameters / outcomes will be used: - Neurophysiological findings: 1) amplitude and latency values for N2, P3, and ERN EEG / ERP components, 2) alpha band (7.5-13Hz) EEG analysis for the oscillating alpha-lateralisation task. - Psychophysiological results: heartbeat interval (IBI SD) and frequency spectral analysis (LF, HF, ratio) of heart rate variability (HRV) data. -Behavioural outcomes: 1) Response times (RT), 2) Accuracy scores.	—

Measure

Time frame

For the cross-sectional comparison of depressed patients, patients in remission, and healthy subjects, we will use the following outcomes: - Response times on the Stroop test with emotional facial expressions. - Number of items correctly remembered emotional faces or scenes. - Direct measurement of attention for emotional faces through the eye-tracking test. To compare the effect of a mindfulness course vs. a waiting list control group, the following parameters / outcomes will be used: - Neurophysiological findings: 1) amplitude and latency values for N2, P3, and ERN EEG / ERP components, 2) alpha band (7.5-13Hz) EEG analysis for the oscillating alpha-lateralisation task. - Psychophysiological results: heartbeat interval (IBI SD) and frequency spectral analysis (LF, HF, ratio) of heart rate variability (HRV) data. -Behavioural outcomes: 1) Response times (RT), 2) Accuracy scores.

—

Secondary

Measure	Time frame
none	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)