Novel diagnostic markers for necrotising enterocolitis in the premature infant

Novel diagnostic markers for necrotising enterocolitis in the premature infant - NoNEC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34937

Enrollment

Registered

2010-04-09

Start date

2010-10-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

necrotising enterocolitis

Interventions

None listed

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: Neonates with suspected necrotising enterocolitis

Exclusion criteria

Exclusion criteria: Abdominal wall defects, hyperbilirubinaemia necessitating intensive phototherapy

Design outcomes

Primary

Measure	Time frame
urine I-FABP/Claudin to Creatinine ratio, tissue oxygenation as measured via NIRS	—

Secondary

Measure	Time frame
inflammatory/metabolic markers such as WBC, CRP, TNFa, IL6 and IL10 and lactate/base excess as measured in blood and urine, location/quantity of FABP*s in the resected bowel and faecal cultures.	—

Countries

Netherlands

Outcome results