obesitas
Conditions
Interventions
Cross-over experiment with 2 gastric emptying measurements per subject. In one
of the conditions a fixed amount of 500g of the low viscosity product will be
consumed, in the other condition a fixed
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: *Apparently healthy, self reported *Young adult males: 18-30 year *Normal weight: BMI 18.5-25 kg/m2 *Used to eating breakfast (> 5 times per week) *
Exclusion criteria
Exclusion criteria: *Loss of appetite *Weight change of >5kg during the last 2 months *Being on a weight loss diet *On a prescribed diet that interferes with the study foods *Bowel or stomach disorder *Diabetes or thyroid disorder *Food intolerance or allergy for foods that are provided during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study outcome is gastric emptying (and the variation in that measurement). Gastric emptying will be measured with a non-invasive breath test. The subject will come in fasting state to the research centre and ingest the test product which is labelled with 13C. The test foods consist of 2 chocolate flavoured milk products, differing in viscosity. Breath samples will be collected before consumption of the food and at 15 minute intervals during 3 hours. Breath samples will be analyzed on concentration of 13C. 13C recovery (T1/2 and Tlag) will be used as a measure for gastric emptying. | — |
Secondary
| Measure | Time frame |
|---|---|
| Appetite and wellbeing ratings will be measured during the test by means of Visual Analogue Scales. | — |
Countries
Netherlands
Outcome results
None listed