The role of diaphragm muscle EMG monitoring on respiratory physiology in mechanically ventilated patients with ARDS: a pilot study

The role of diaphragm muscle EMG monitoring on respiratory physiology in mechanically ventilated patients with ARDS: a pilot study - Diaphragm muscle EMG during mechanical ventilation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34914

Enrollment

Registered

2010-08-26

Start date

2011-01-12

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lung injury

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Intubated, mechanically ventilated adult patients • Meeting criteria for ARDS: o Acute decrease in the ratio of partial pressure of arterial oxygen to fraction of inspired oxygen to 300 mmHg or less o Bilateral pulmonary infiltrates on chest radiography consistent with edema o No clinical evidence of left atrial hypertension • Mean arterial blood pressure >65 mmHg (with or w/o vasopressors).

Exclusion criteria

Exclusion criteria: • Pregnancy (due to altered position of the diaphragm) • Increased intracranial pressure, or clinical suspicion of elevated intracranial pressure (i.e. neurotrauma) • Contra-indication for naso-gastric feeding tube • Diagnosed neuro-muscular disorder before ICU admission • Recent (

Design outcomes

Primary

Measure	Time frame
• Pressure-time product of the diaphragm (measure for work of breathing) • Patient-ventilator asynchrony index	—

Secondary

Measure	Time frame
• Transpulmonary pressure (measure for lung stretch) • Transdiaphragmatic presure (measure for diaphragm function) • Oxynation index (arterial oxygen tension / fraction of inspired oxygen) • Respiratory compliance (tidal volume / plateau pressure - toal PEEP) • Dead space ventilation	—

Countries

Netherlands

Outcome results