Acceptance and Commitment Therapy vs. Cognitive Therapy for the treatment of Major Depressive Disorder

Acceptance and Commitment Therapy vs. Cognitive Therapy for the treatment of Major Depressive Disorder - ACT vs. CT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON34875

Enrollment

Registered

2010-09-20

Start date

2010-05-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder

Interventions

The study concerns two psychological treatments: • 16-20 sessions of cognitive therapy • 16-20 sessions of Acceptance en Commitment Therapy

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1) Meeting DSM-IV criteria for MDD 2) between the ages of 18 and 65-years-old 3) having sufficient fluency in Dutch to complete treatment and research protocol 4) Participants using prescribed anti-depressant medication are required to be on a stable dose for at least 2 weeks before the beginning of treatment and remain on this dose throughout the treatment.

Exclusion criteria

Exclusion criteria: 1) DSM-IV criteria for bipolar disorder (past and/or present) 2) psychotic disorders 3) substance dependence disorders (current or within the past 6 months), or 4) organic brain syndrome. 5) borderline or antisocial personality disorder

Design outcomes

Primary

Measure	Time frame
The main dependent variables are 1) Self-reported distress on the Beck Depression Inventory (BDI; Beck et al., 1961), and 2) Clinicial rated distress on the Hamilton Rating Scale for Depression (HRSD; Hamilton, 1960).	—

Secondary

Measure	Time frame
Additionele afhankelijke variabelen: - Quality of life: Eurohis Quality of Life Scale (Eurohis; Power, 2003). 1. Proces measures for ACT 1a. Decentering subschale of the Experiences Questionnaire (EQ; Fresco et al., 2007) 1b.Acceptance and Action Questionnaire (AAQ-II) (Hayes et al., unpublished; Dutch version: Jacobs, Kleen, de Groot, A-Tjak, 2008). 2. Proces measures for CT 2a. Dysfunctional Attitude Scale-revised (DAS-17; de Graaf et al., 2009) 2b. Implicit Attitude Test (IAT; Greenwald et al., 1998) adjusted for depression. Other (moderator/mediator) variabeles: • Credibility/Expectancy Questionnaire (CEQ; Devilly & Borkovec, 2000. • Working Alliance Inventory (WAI; Horvath & Greenberg, 1989) The Relationship Scales Questionnaire (RSQ; Griffin, & Bartholomew, 1994). • Cluster C personality traits will be assessed with the Personality Disorder Beliefs Questionnaire (PBQ; Arntz et al., 2004).	—

Measure

Time frame

Additionele afhankelijke variabelen: - Quality of life: Eurohis Quality of Life Scale (Eurohis; Power, 2003). 1. Proces measures for ACT 1a. Decentering subschale of the Experiences Questionnaire (EQ; Fresco et al., 2007) 1b.Acceptance and Action Questionnaire (AAQ-II) (Hayes et al., unpublished; Dutch version: Jacobs, Kleen, de Groot, A-Tjak, 2008). 2. Proces measures for CT 2a. Dysfunctional Attitude Scale-revised (DAS-17; de Graaf et al., 2009) 2b. Implicit Attitude Test (IAT; Greenwald et al., 1998) adjusted for depression. Other (moderator/mediator) variabeles: • Credibility/Expectancy Questionnaire (CEQ; Devilly & Borkovec, 2000. • Working Alliance Inventory (WAI; Horvath & Greenberg, 1989) The Relationship Scales Questionnaire (RSQ; Griffin, & Bartholomew, 1994). • Cluster C personality traits will be assessed with the Personality Disorder Beliefs Questionnaire (PBQ; Arntz et al., 2004).

—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)