patients with 45 Patients with Turner syndrome X.
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with Turner syndrome who have been participating in one of the following studies: MEC: GHTUR/BPD/13NL and MEC: GHTUR/BPD/12NL (the inclusion criteria of the original protocols are described in the protocol at page 14).
Exclusion criteria
Exclusion criteria: The exclusion criteria are those of the original protocols: MEC: GHTUR/BPD/13NL and MEC: GHTUR/BPD/12NL ((the exclusion criteria of the original protocols are described in the protocol at page 15).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency of hidden mosaicism, including Y chromosomal material, in 45,X females. The effects of different GH regimens will be analyzed to a background of genotypic variation of the sex chromosomes and the growth hormone receptor. The clinical parameters (aortic diameter and distensibility, congenital cardiac malformations, lipid profile, final height and final height gain) are already assessed in the original studies. | — |
Secondary
| Measure | Time frame |
|---|---|
| not applicable. | — |
Countries
Netherlands
Outcome results
None listed