Effect of preload reduction through intermittend hemodialysis or continuous veno-venous hemofiltration on microcirculatory perfusion in patients with chronic kidney failure and critically ill patients

Effect of preload reduction through intermittend hemodialysis or continuous veno-venous hemofiltration on microcirculatory perfusion in patients with chronic kidney failure and critically ill patients - Fluid management and peripheral perfusion

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34825

Enrollment

Registered

2010-04-13

Start date

2010-05-05

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intensive care patienten microcirculatory perfusion renal replacement therapie

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: We will include two patientspopulations, firstly patients undergoing chronic intermittend renal replacement therapy in an outpatient clinic setting. Secondly we will include patients admitted to the intensive care unit who receive continuous veno-venous hemofiltration with ultrafiltration. Of both populations we will include 20 patients. Inclusion criteria for patients receiving chronic intermittend renal replacement therapy: - Age above 18 yrs - Admitted for intermittend hemodialysis.;Inclusioncriteria for patients admitted to the intensive care unit who receive continuous veno-venous hemofiltration. - Age above 18 yrs. - Clinical indication for continuous veno-venous hemofiltration with ultrafiltration

Exclusion criteria

Exclusion criteria: Exclusion criteria for patients receiving chronic intermittend renal replacement therapy: - Circumstances making it impossible to perform sublingual measurements, like bleeding of the oral cavity. - Patients who require no or only small amounts of ultrafiltration during hemodialysis. ;Exclusioncriteria for patients admitted to the intensive care unit who receive continuous veno-venous hemofiltration. - Circumstances making it impossible to perform sublingual measurements, like bleeding of the oral cavity

Design outcomes

Primary

Measure	Time frame
The main study parameter is the sublingual microcirculatory perfusion.	—

Countries

Netherlands

Outcome results