Chronic Chilblains
Conditions
Interventions
The intervention which is compared to the placebo consists of the thin
application of betamethasonvaleraat cream 0,1 % twice a day for 6 weeks where
the perniones laesions are located .
Sponsors
Huisartspraktijk Souwer
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 18 years or older; able to understand and follow instructions; Complaints of chronic pernio for at least 3 weeks at inclusion: itching or painfull blue-red discolorated laesions at fingers and/or toes, other lokalisations at the feet or lateral side of the thigs ("the Kibes"). The laesions may be swollen ans ulceration may be pressent but not obligitory. Onset of complaints is in the period november to februari.
Exclusion criteria
Exclusion criteria: Known inflamatory disease (RA, SLE et cetera); pregnancy; lactation; actual use of a calcium antagonist, use of corticosteroïd containing cream in the past four weeks, skin defects at the skinparts to treat.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We consider the intervention effective if a reduction of the experienced complaints or is discovered, displayed in a decline of the score "complaint" with at least 10 mm on the visual analogue scale concerned. "Complaint" is defind as Max (itch,pain): the Vas score for or itch or pain, depending on the highest score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary we register scores for impairement and the experienced side effects, skin irritation, and symptoms of skin atrophy: purpurae, inclination to bleed and depigmentation. | — |
Countries
Netherlands
Outcome results
None listed