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The role of evaluative learning in the development and persistence of posttraumatic stress disorder

The role of evaluative learning in the development and persistence of posttraumatic stress disorder - Evaluative learning and posttraumatic stress

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON34729
Enrollment
180
Registered
2010-08-30
Start date
2010-12-13
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posttraumatic Stress Disorder (PTSD)

Interventions

None listed

Sponsors

Universiteit Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Study 1 (Danger and disgust-associations after burglary): 100 healthy participants; a) adult (* 18 years); b) Dutch fluency; c) exposed to burglary in own home without confrontation; and d) burglary occurred not more than one month earlier. Study 2 (Danger and disgust-associations after assault): 80 participants; a) adult (* 18 years); b) Dutch fluency; c) having experienced sexual or physical assault by a male perpetrator at least 3 months earlier and after the age of 14 (this age is typically used to distinguish childhood and adulthood in studies of abuse; see e.g., Linton et al., 1996), of whom 40 participant with d) PTSD diagnosis for PTSD group (N

Exclusion criteria

Exclusion criteria: For study 1 (Danger and disgust-associations after burglary), there are no exclusion criteria. Exclusion criteria for study 2 (Danger and disgust-associations after assault) are: a) assault in childhood (

Design outcomes

Primary

MeasureTime frame
The main outcome is PTSD symptom severity assessed with a questionnaire.

Secondary

MeasureTime frame
Secondary outcome variables in both study 1 and 2 are anxiety and depression symptoms assessed with questionnaires, and past and present DSM IV psychiatric disorders assessed with semi-structured interviews. Study 2 also uses rinsing behaviour after trauma-related imagery and physical intimacy as a secondary outcome variable. In both studies, independent variables include fear-related vulnerabilities (neuroticism, anxiety sensitivity), disgust-related trait vulnerabilities (disgust propensity and sensitivity, contamination sensitivity), disgust/fear-related associations, and affective priming.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)