obesity overweight
Conditions
Interventions
Part I: subjects stay for each condition, for 3 circadian cycles, in the
absence of time cues, in a controlled situation under controlled energy balance
conditions in a respiration-chamber. In order
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Subjects have to be in good health, weight stable, non-smokers, not using medication, not have sleep problems, and at most moderate alcohol users. They have to be overweight, BMI 25-29 kg/m2, adolescent and young adult, age 18-30 yrs, men, who are evening people.
Exclusion criteria
Exclusion criteria: BMI 30 kg/m2, women, morningpeople, age 30 year, using any kind of medication, smokers, sleep problems and excessive use of alcohol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| With the experimental approach the following outcome will appear: 1) Effects of light- and food-entrained circadian misalignment versus circadian-alignment on: (i) circadian patterns of parameters associated with circadian rhythm, and of parameters associated with food intake patterns, namely patterns of concentrations of the following blood-parameters: melatonin, leptin, glucose, insulin, ghrelin, GLP-1; VAS-ratings on appetite sensations; VAS-ratings on the stress-related POMS- and STAI-questionnaires. (ii) food choice, food reward, and energy intake. (iii) circadian patterns of energy expenditure and its components; (iv) substrate oxidation; macronutrient-balance; (v) circadian patterns of body-temperature; (vi) physical activity and its circadian patterns; (vii) circadian patterns of heart rate viii sleep quality | — |
Countries
Netherlands
Outcome results
None listed