chronische pijn (bij patienten) chronic pain skin sensitivity
Conditions
Interventions
No medication will be administered.
Sponsors
PRA International EDS
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with chronic pain Gender: male and female Age: between 18 and 80 years of age, inclusive Pathology: chronic pain history of 3 months or longer pain has been considered by a physician to be either of neuropathic origin, or resulting from nerve damage due to diabetes mellitus, of postherpetic neuralgia, of phantom pain (i.e., pain resulting from an amputed limb) Weight: no specific criteria;Healthy volunteers Gender: male and female Age: between 18 and 80 years of age, inclusive Weight: no specific criteria
Exclusion criteria
Exclusion criteria: Patients with chronic pain: - mental handicap;Healthy volunteers: - history of chronic pain - history of neurological disorders - history of psychiatric disorders - regular use of pain medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Criteria for evaluation Assessments: Detection thresholds and pain thresholds for thermal and mechanical stimulation, number of paradoxical heat sensations during the thermal sensory limen procedure, mechanical pain sensitivity, dynamic mechanical allodynia, temporal pain summation, vibration detection threshold, pressure pain threshold. Statistical methods: Z-scores will be calculated for each QST parameter. | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed