Towards cost-effective diagnostic management of patients with primary aldosteronism: adrenal vein sampling or CT-scan?

Towards cost-effective diagnostic management of patients with primary aldosteronism: adrenal vein sampling or CT-scan? - Computed Tomography vs. Adrenal Vein Sampling in primary aldosteronism

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON34699

Enrollment

200

Registered

2010-06-14

Start date

2010-09-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

conn's disease primary aldosteronism

Interventions

APA is diagnosed by asymmetric adrenal aldosterone production as found by AVS in one group or by a visible adenoma with normal contralateral gland when assessed by CT in the other group. BAH will be

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients >

Exclusion criteria

Exclusion criteria: pregnancy

Design outcomes

Primary

Measure	Time frame
The criterion ('gold') standard of correct strategy will be medication use after one year of follow-up.	—

Secondary

Measure	Time frame
Secondary endpoints will be costs of each strategy, quality of life, serum potassium, proportion of patients with normal blood pressure with or without medication, and normalization of aldosterone (after Adx only). Costs of each strategy consist of immediate costs and long-term extrapolated costs of diagnosis and surgical and medical treatment in both arms.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)