Altered brain processing of rectal sensation in children with functional fecal incontinence.

Altered brain processing of rectal sensation in children with functional fecal incontinence. - fMRI and rectal barostat

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34690

Enrollment

Registered

2010-12-14

Start date

2010-11-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

functional constipation and fecal incontinence

Interventions

None listed

Eligibility

Age

12 Years to 17 Years

Inclusion criteria

Inclusion criteria: Adolescents between 12-18 years old who suffer from fecal incontinence for at least 2 years and who fulfill the ROME III criteria for functional constipation or functional non-retentive fecal incontinence will be eligible for enrolment.;Functional constipation is defined by at least 2 of the following criteria: 1) spontaneous defecation frequency

Exclusion criteria

Exclusion criteria: Patients with 1) organic causes of constipation, including Hirschsprung*s disease, muscle disorders, prior recto-anal surgery, spina bifida, mental retardation or hypothyroidism, 2) intercurrent illness or active colitis, 3) known allergy to latex or polyethylene, 4) incapable to verbally cooperate or 5) claustrophobia will be excluded from the study.

Design outcomes

Primary

Measure	Time frame
The cerebral regions and level of brain activity in children with FC and FNRFI during rectal sensation of urge to defecatie.	—

Secondary

Measure	Time frame
Differences in cerebral activity between FC and FNRFI.	—

Countries

Netherlands

Outcome results