The excitability of peripheral nerves following acute stroke: A 6-month follow-up study using neurophysiological and clinical tests

The excitability of peripheral nerves following acute stroke: A 6-month follow-up study using neurophysiological and clinical tests - EXIST

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34667

Enrollment

116

Registered

2010-01-15

Start date

2010-02-02

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular accident stroke

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - A first-ever ischemic stroke - Hemiplegia, including weakness of the hand muscles - Stroke onset

Exclusion criteria

Exclusion criteria: - Non stroke-related sensory or motor impairments - Any peripheral lesion of the median nerve, such as nerve root compression syndrome, cervical spondylosis, carpal tunnel syndrome, or other peripheral neuropathy revealed by neurological examinations and electrodiagnostic tests - Any history of other diseases or treatment that might have affected the peripheral nerve

Design outcomes

Primary

Measure	Time frame
For neurophysiology: estimates of the number of functioning motor units (MUNEs) and excitability variables obtained with threshold tracking techniques. For clinical stroke assessment: questionnaires (NIHSS) and scales (modified Rankin scale, Barthel index), CT, the TOAST classification of stroke subtype, and an evaluation of cardiovascular risk factors.	—

Secondary

Measure	Time frame
N.v.t.	—

Countries

Netherlands

Outcome results