Effects of postprandial hyperglycemia on aortic elasticity in impaired glucose tolerance and diabetes mellitus type 2

Effects of postprandial hyperglycemia on aortic elasticity in impaired glucose tolerance and diabetes mellitus type 2 - Postprandial hyperglycemia and aortic elasticity

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON34650

Enrollment

Registered

2010-03-12

Start date

2010-05-13

Completion date

Unknown

Last updated

2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

elasticity aorta

Interventions

Oral glucose tolerance test

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: For all: Age: 18-65 years, informed consent. Patients with T2DM: untreated or treated with oral glucose lowering agents HbA1c

Exclusion criteria

Exclusion criteria: Healthy controls and impaired glucose tolerance: grade 2 or 3 hypertension at screening (ESC guidelines); use of glucose lowering mediaction/ statins or antihypertensives; any significant chronic disease; smoking; contra-indications MRI Patients with type 2 diabetes: tension: >140/90 mmHg; use of insulin/ thiazolidinediones/ smoking/ contra-indications MRI

Design outcomes

Primary

Measure	Time frame
Pulse Wave Velocity	—

Secondary

Measure	Time frame
Heart Rate variability Glucose and insulin levels Cardiac function	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)