Effects of a 6-month exercise program on ectopic fat accumulation in heart, liver and skeletal muscle in patients with type 2 diabetes mellitus.

Effects of a 6-month exercise program on ectopic fat accumulation in heart, liver and skeletal muscle in patients with type 2 diabetes mellitus. - Exercise and ectopic fat accumulation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON34635

Enrollment

Registered

2010-02-22

Start date

2010-02-23

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes mellitus type 2

Interventions

Exercise program during 6 months All patients will receive an individualised exercise program. Every month patients will report the amount of exercise, details on diet and they will carry the Sense

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Group A: Diabetes mellitus type 2, Age>18 years, informed consent Group B: Age and BMI matched female healthy controls, Age >18 years, informed consent

Exclusion criteria

Exclusion criteria: Group A: (congenital) heart disease; liver disease (increased ALAT and GGT); renal disease (creatine above reference level); muscular diseases; BMI > 36 kg/m2; MRI contra-indications;Group B: same as group B + no diabetes mellitus + no pregnancy

Design outcomes

Primary

Measure	Time frame
Hepatic, myocardial and muscle triglyceride content and cardiac function	—

Secondary

Measure	Time frame
Antropometric measurements, biochemical values and basal metabolic rate.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)