Dual Energy Computer tomography in acute and chronic myocardic infarction.

Dual Energy Computer tomography in acute and chronic myocardic infarction. - Demi study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34601

Enrollment

140

Registered

2011-01-13

Start date

2011-01-25

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial infarction

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with acute myocardial infarction - Age>40 years - Onset of symptoms no more than 14 days before CT and MRI;If Acute no ST-elevation myocardial infarction (NSTEMI) - Clinical presentation: rest angina/ new-onset severe angina/ increasing angina - ST segment depression >=0.05mV or inverted T waves >=0.2mV - Detection of troponine T or CK elevation over a period of 24-48 hours - Imaging evidence of new loss of viable myocardium or new regional wall motion abnormalities;Patients with chronic myocardial infarction - Age>40 years - Impaired left ventricle ejection fraction - Regional myocardial dysfunction

Exclusion criteria

Exclusion criteria: Clinical contraindications: - Ongoing ischemia - Relevant arrhythmias - Coronary artery by-pass graft (CABG) - Impaired renal function (serum creatinine>120 *mol/l or GFR

Design outcomes

Primary

Measure	Time frame
Assessment of the presence of myocardial infarction per coronary distribution on Dual Energy CT images, using MR as the reference standard.	—

Secondary

Measure	Time frame
assessment of the presence of no-reflow areas per coronary distribution on Dual Energy CT images, using MR as the reference standard visual-semiquantitative analysis of scar tissue manual planimetry for the quantification of the scar tissue	—

Countries

Netherlands

Outcome results