metabool syndroom ANCA-associated vasculitis (inflammation of the vessel wall caused by the own immune system) and Metabolic syndrome (combination of risk factors that can lead to diseases that involve the heart or blood vessels)
Conditions
Interventions
None listed
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients: - Age: > 18 years - Diagnosis: ANCA-associated vasculitis according to the classification criteria of Watts et al. - Known with the disease for more than 1 year.;Healthy controles: - Partner of included patient.
Exclusion criteria
Exclusion criteria: Patients: - Patients do not fulfil the classification criteria of Watts et al. - Under aged and legally incapable. - Immunosuppressive medication: > 15 mg prednison;Healthy controles: - Under aged and legally incapable
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary study parameter: Is the prevalence of the metabolic syndrome (NCEP-criteria) increased within ANCA-associated patients compared to healthy controls? | — |
Secondary
| Measure | Time frame |
|---|---|
| Secundary study parameters: - Do relapses occur more frequently within ANCA-associated vasculitis patients who meet the criteria for the metabolic syndrome compared to ANCA-associated vasculitis patients without the metabolic syndrome? - Are the ANCA levels persistently higher within ANCA-associated vasculitis patients who meet the criteria for the metabolic syndrome? - Is the C-reactive protein (CRP) persistently higher within ANCA-associated vasculitis patients who meet the criteria for the metabolic syndrome? - Does proteinuria occur more often within ANCA-associated vasculitis patients who meet the criteria for the metabolic syndrome? | — |
Countries
Netherlands
Outcome results
None listed