Identification of psychometric and biological markers to assess androgen and serotonergic sensitivity in relation to sexual functioning in women.

Identification of psychometric and biological markers to assess androgen and serotonergic sensitivity in relation to sexual functioning in women. - Androgen sensitivity in women.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34558

Enrollment

200

Registered

2010-12-02

Start date

2010-12-15

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Sexual Dysfunction

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Provision of written informed consent; 2. Female 21-70 years of age; 3. Healthy according to normal results of medical history 4. Subject must be heterosexually oriented; 5. BMI >= 18 and

Exclusion criteria

Exclusion criteria: 1. Subjects who have had hand surgery interfering with measurement of digit lengths; 2. Subjects with musculoskeletal conditions affecting the measurements of digit lengths; 3. Known conditions associated with abnormal prenatal androgen exposure, namely congenital adrenal hyperplasia and complete androgen insensitivity syndrome; 4. Positive drug test and/or positive alcohol test; 5. Subjects with dyslexia; 6. Subjects who are color-blind; 7. Positive urine pregnancy test; 8. Use of oral contraception containing anti-androgens (e.g. Diane 35; Minerva); 9. Use of oral contraception containing 50 µg estrogen or more; 10. Homosexual orientation.

Design outcomes

Primary

Measure	Time frame
1. [CAG]n 2. Calculated second to fourth digit ratio 3. Pre-attentional bias for erotic stimuli (Stroop task) 4. Blood serum free testosterone levels	—

Secondary

Measure	Time frame
1. Blood serum levels ADT-G, 3a-diol-G, DHEA and DHEA(s) 2. Genotype SERT and 5HT1a receptor 3. Questionnaires: SAQ, SSEQ and SMQ	—

Countries

Netherlands

Outcome results