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Salivary cortisol in children with asthma and/or rhinitis: effect of topical steroids and correlation with symptoms and lungfunction

Salivary cortisol in children with asthma and/or rhinitis: effect of topical steroids and correlation with symptoms and lungfunction - Effect of topical steroids on salivary cortisol level in children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON34524
Enrollment
40
Registered
2010-09-06
Start date
2011-03-03
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adrenal function cortisol level

Interventions

None listed

Sponsors

Medisch Centrum Leeuwarden
Lead Sponsor

Eligibility

Age
2 Years to 17 Years

Inclusion criteria

Inclusion criteria: children 6-18 years newly referred children who are diagnosed with asthma and/or rhinitis and who are not already using topical steroids children with stable asthma and/or rhinitis in whom topical steroids can be tapered down to zero according to international guidelines

Exclusion criteria

Exclusion criteria: informed consent is not obtained if a child is unwilling to participate during the study a chronic medical condition other than asthma and/or rhinitis use of oral steroids in the past 3 months use of concurrent medication which may potentially affect steroidmetabolism

Design outcomes

Primary

MeasureTime frame
difference in salivary cortisol level before and during or after treatment with topical steroids

Secondary

MeasureTime frame
correlation of salivary cortisol, symptoms of asthma, and lungfunction

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)