The effects of a single dose of tryptophan dietary supplementation on cognition and mood in the follicular and luteal phase of the menstrual cycle

The effects of a single dose of tryptophan dietary supplementation on cognition and mood in the follicular and luteal phase of the menstrual cycle - tryptophan, cognition, and menstrual cycle

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON34501

Enrollment

Registered

2010-10-22

Start date

2011-03-22

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

geen healthy participants

Interventions

Two groups (one follicular and one luteal

both n=20) receive 4 capsules containing 400 mg tryptophan, resulting in a total dose of 1.6 g tryptophan. Two groups (one follicular and one luteal

both n=20) receive 4 placebo capsules.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy women, Dutch-speaking Age 18-30 BMI 18-35 Regular menstrual cycle (22-35 days)

Exclusion criteria

Exclusion criteria: Use of sex hormones or hormonal contraceptives Use of tryptophan supplements Medical or psychiatric illness, or medication use Breastfeeding Smoking of drug use

Design outcomes

Primary

Measure	Time frame
Accuracy and reaction time on the facial expression recognition test (cognitive test).	—

Secondary

Measure	Time frame
Scores on other cognitive tests and questionnaires that measure mood and cognitive reactivity.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)