Non-Alcoholic Fatty Liver Disease: non-invasive diagnosis with MR Elastography and MR Spectroscopy

Non-Alcoholic Fatty Liver Disease: non-invasive diagnosis with MR Elastography and MR Spectroscopy - MRE-NAFLD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34446

Enrollment

Registered

2010-09-23

Start date

2010-10-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

accumulation of fat in the liver non-alcoholic fatty liver disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients over 18 years of age - Patients with biopsy-proven NAFLD/NASH or with suspected NALFD/NASH who are scheduled for liver biopsy. - Liver biopsy

Exclusion criteria

Exclusion criteria: - Patients under 18 years of age - Alcohol consumption of >3 units per dag for males and >2 units per day for females - Patients with contra-indications for MRI (use of standard MRI checklist) - Patients with extreme obesity (will not fit in the MRI)

Design outcomes

Primary

Measure	Time frame
* Elasticity values (kPa) for simple steatosis group vs. NASH group * Viscosity values (kPas) for simple steatosis group vs. NASH group Liver fat content (% of liver volume) for simple steatosis group vs. NASH group * FibroScan measurement (kPa) for simple steatosis group vs. NASH group	—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results