The development of secondary hyperalgesia after high frequency electrical stimulation (HFS) of the skin in patients with and without chronic postoperative pain after inguinal hernia repair.

The development of secondary hyperalgesia after high frequency electrical stimulation (HFS) of the skin in patients with and without chronic postoperative pain after inguinal hernia repair. - Sec.hyperalgesia in patients with chronic pain after inguinal hernia repair

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34441

Enrollment

Registered

2010-07-20

Start date

2010-08-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic discomfort chronic pain

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Presence of chronic pain as a result of inguinal hernia repair (local pain) for the experimental group No pain aftere inguinal hernia repair for the control group 6 to 7 years after surgery (operated between April 2001 and March 2003) Aged 18 - 65 year Men Ability to give informed consent Ability to understand the research and follow the instructions during the experiment

Exclusion criteria

Exclusion criteria: Presence or history of other neurological or major psychiatric diseases Regular intake of medication affecting potentially brain function or EEG signal (e.g., psychopharmacological drugs; morphine, anti-psychotics, anti-depressives, anti-epileptica, benzodiazepines) Regular legal or illegal drug intake Any pre-existing type of chronic pain syndrome No participation in other research

Design outcomes

Primary

Measure	Time frame
The difference between post minus pre HFS measures regarding the subjective intensity (VAS) and the event-related potential amplitude compared between patients with chronic pain and patients without pain. The nature of pain will be classified using the DN4 (Douleur Neuropathique en 4 Questions).	—

Secondary

Measure	Time frame
To investigate the nature of the pain, i.e. whether it is of neuropathic origin or not. To document the presence of depressive symptoms. To document the amount of catastrophising. To document the quality of life .	—

Countries

Netherlands

Outcome results