Thrombocyte dysfunction during cardiac surgery
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Elective CABG-procedure with use of extracorporale circulation Group 1: Minimum of 5 days use of clopidogrel and aspirin until day of procedure. Group 2: Minimum of 5 days use of aspirin until the day of procedure, but no clopidogrel use for at least 5 days prior to the procedure.
Exclusion criteria
Exclusion criteria: Use of coumarines or (low molecular weight) heparin Clinical or laboratory signs of hemorrhagic diathesis Cardiac failure Renal insufficiency or dialysis Liver failure Chronic alcoholism Age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcome if the different labortory tests of platelet function Blood loos during and within 24 hours after the surgical procedrue Transfused number of units during and within 24 hours after the surgical procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between the different thrombocyte function tests in the two studied populations | — |
Countries
Netherlands