Extended trough level measurement with extended release formulation of tacrolimus

Extended trough level measurement with extended release formulation of tacrolimus - Advadal

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34374

Enrollment

Registered

2011-01-06

Start date

2011-12-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal transplantation

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Recipient of a renal graft 2. Age: 18 years or older 3. Informed consent 4. At least 2 months after renal transplantation 5. Treatment with tacrolimus OD 6. Tacrolimus trough levels within the target range (5-10 ug/l) at two subsequent occasions.

Exclusion criteria

Exclusion criteria: 1. Severe diarrhea (> 3 stools per day) 2. Change in tacrolimus dosage within one week prior to inclusion

Design outcomes

Primary

Measure	Time frame
The difference between trough levels measured at 24 hours and at 32 hours after taking of tacrolimus OD.	—

Secondary

Measure	Time frame
The extent of correlation between these two measurements	—

Countries

Netherlands

Outcome results