Computer based training of executive functions in children with an autism spectrum disorder.

Computer based training of executive functions in children with an autism spectrum disorder. - Executive functioning training in autism.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON34346

Enrollment

102

Registered

2010-09-23

Start date

2010-09-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autism autism spectrum disorder

Interventions

In short, 102 children with autism, 8 to 12 years of age, and an estimated IQ above 80 will participate in a randomized controlled clinical trial. Children will be randomly assigned to one of three

WM training, CogF training or no training. The children will play the game, in which these training conditions are embedded. The total number of training sessions is 25, with a fixed duration of 40

the level is and will remain very low, so no EF is actually being trained. This condition will however apply to fastness of reaction, attention and concentration.

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: 1) A diagnosis of an autism spectrum disorder 2) A diagnosis confirming score on the Social Responsiveness Scale and ADI-R. 3) Age between 8-12 years 4) IQ above 80

Exclusion criteria

Exclusion criteria: 1) Epilepsy

Design outcomes

Primary

Measure	Time frame
1) Cognitive flexibility: switchcosts (reaction time (RT) on switchtrials compared to non-switchtrials) on the Gender/emotion switch task and Number switch task). 2) Working memory: number correct on the Corsi Block Tapping Task and n-back task. 3) AD/HD symptoms: score on the Disruptive Behavior Disorder rating scale (DBD). 4) Social skills: score on the Children*s Social Behavior Questionnaire (CSBQ). See studyprotocol for further information about these tasks and questionnaires.	—

Measure

Time frame

1) Cognitive flexibility: switchcosts (reaction time (RT) on switchtrials compared to non-switchtrials) on the Gender/emotion switch task and Number switch task). 2) Working memory: number correct on the Corsi Block Tapping Task and n-back task. 3) AD/HD symptoms: score on the Disruptive Behavior Disorder rating scale (DBD). 4) Social skills: score on the Children*s Social Behavior Questionnaire (CSBQ). See studyprotocol for further information about these tasks and questionnaires.

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Secondary

Measure	Time frame
1) Inhibition: Stop-reaction time on the Stop task. 2) AD/HD symptoms: number correct on the Sustained attention response task (the SART). 3) EF (all) (Behavior Rating Inventory of Executive Function questionnaire (BRIEF). 4) Quality of Life (Pediatric Quality of Life Inventory, PedsQL). ToM (score on the Strange Stories Test), punnishment reward sensitivity (score on the BIS/BAS Questionnaire, RT and number correct on a reward vs. neutral version of the Eriksen flanker paradigm), and motivation (score on the VAS scale) will be included as predictors of improvement as a result of the program. See studyprotocol for further information about these tasks and questionnaires.	—

Measure

Time frame

1) Inhibition: Stop-reaction time on the Stop task. 2) AD/HD symptoms: number correct on the Sustained attention response task (the SART). 3) EF (all) (Behavior Rating Inventory of Executive Function questionnaire (BRIEF). 4) Quality of Life (Pediatric Quality of Life Inventory, PedsQL). ToM (score on the Strange Stories Test), punnishment reward sensitivity (score on the BIS/BAS Questionnaire, RT and number correct on a reward vs. neutral version of the Eriksen flanker paradigm), and motivation (score on the VAS scale) will be included as predictors of improvement as a result of the program. See studyprotocol for further information about these tasks and questionnaires.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)