glucose sensitivity insulin resistance
Conditions
Interventions
The intervention is part of the oral glucose tolerance test (OGTT) and consists
of single administration of 75 g glucose dissolved in 300 ml water.
Sponsors
TNO
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Healthy as assessed by the TNO health and lifestyle questionnaire (short version) 2. Age 65-75 y (boundaries included) at Day 01 of the study 3. Able to perform easy actions on a computer 4. Voluntary participation 5. Having given written informed consent 6. Willing to accept use of all nameless data, including publication, and the confidential use and storage of all data for at least 15 years 7. Willing to accept the disclosure of the financial benefit of participation in the study to the authorities concerned.
Exclusion criteria
Exclusion criteria: 1. Having (a history of) medical or surgical events that may significantly affect the study outcome, including psychiatric disorders, diabetes 2. Use of medication for diabetes 3. Alcohol consumption > 28 units/week for males and > 21 units/week for females 4. Personnel of TNO Quality of Life, their partner and their first and second degree relatives 5. Not having a general practitioner 6. Not willing to accept information-transfer regarding his/her health, like laboratory results, findings at anamnesis and eventual adverse events to and from his general practitioner.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Assessment of peripheral glucose regulation by means of the standard 2-h oral glucose tolerance test (OGTT) 2. Assessment of cognitive performance by means of a computerized validated test system. | — |
Countries
Netherlands
Outcome results
None listed