Coronary artery disease multivessel disease
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - A diagnosis of a STEMI defined by 1/A diagnosis of acute MI defined by chest pain suggestive for myocardial ischemia for at least 30 minutes, with a time from onset of symptoms of less than 12 hours, before hospital admission, 2/ ECG with ST- segment deviation of more than 0.1 mV in 2 or more leads and 3/Positive cardiac troponin T >0.01 *g/l. - Clinical indication for urgent PCI of the infarct related lesion as identified at coronary angiography - Planned staged PCI for a lesion in a non-infarct related vessel - Verbal followed by written informed consent - 18 years or older
Exclusion criteria
Exclusion criteria: - Presence of cardiogenic shock - Implantation or planned implantation of an intra-aortic balloon pump - Failed reperfusion of the infarct related vessel (>30% residual stenosis and less than TIMI 3 coronary flow) - No staged PCI possible - Need for coronary artery bypass grafting - No suitable anatomy of the non-IRV (Left main stenosis of >50%, Diameter
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy defined as difference between FFR in the acute phase and second procedure (delta FFR). | — |
Secondary
| Measure | Time frame |
|---|---|
| Feasibility defined as completion of the FFR protocol and safety measured as procedural time, contrast volume used and procedural complications (bleeding, dissection, perforation, reinfarction). | — |
Countries
Netherlands
Outcome results
None listed