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Modulation of Somatosensory Stimulus Evoked Potentials and Pain by Self-Touch

Modulation of Somatosensory Stimulus Evoked Potentials and Pain by Self-Touch - Modulation of SEPs and Pain

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON34275
Enrollment
40
Registered
2011-01-21
Start date
2011-02-14
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pijn nociception pain

Interventions

None listed

Sponsors

Universiteit Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Right-handed

Exclusion criteria

Exclusion criteria: n/a

Design outcomes

Primary

MeasureTime frame
The main study parameter in Experiment 1 is the somatosensory evoked potential recorded bilaterally from EEG electrodes over the primary and secondary somatosensory cortices. In particular, we are interested in differences between ipsilateral SEPs evoked during self-touch as compared to external touch. These differences would indicate inter-hemisphere interaction as a result of self-touch. Similarly, the main study parameter in Experiment 2 is the difference in the pattern of evoked potentials whilst subjects are experiencing an illusion of mild thermal pain, recorded on the entire scalp during self-touch as compared to external touch.

Secondary

MeasureTime frame
We will not have secondary study parameters. However, we will analyze several distinct characteristics of the evoked SEPs (Exp 1) and ERPs (Exp 2), including raw waveforms, trial-locked synchronization, and interhemispheric coherence.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)