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Physical exercise program as an adjuvant therapy for hematopoietic stem cell transplantation: a pilot study

Physical exercise program as an adjuvant therapy for hematopoietic stem cell transplantation: a pilot study - Exercise and stem cell transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON34271
Enrollment
30
Registered
2010-12-24
Start date
2011-03-02
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

(non) Hodgkin's disease hematopoietische malignicies Kahler's diseases leukemia

Interventions

The intervention group receives an individually adjusted physical exercise program of one hour duration which will be administered two times per week during the 6 weeks prior to the HSCT. The progra
the maximum amount of weight one can lift in a single repetition for a given exercise). By using a lighter test load and a small number of repetitions the 1 RM can be calculated based on existing ta

Sponsors

Universitair Medisch Centrum Sint Radboud
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Diagnosed with acute or chronic leukemia, Hodgkin*s Lymphoma, non-Hodgkins*s Lymphoma or Multiple Myeloma; - Scheduled to undergo an allogenic or autologous HSCT; - No cardiovascular contra-indication to engage in physical activity programs as checked by the Physical Activities Readiness Questionnaire (PAR-Q) (Thomas et al 1992), and/or no other physical limitations for physical exercise programs; - Sufficient knowledge of the Dutch language; - Approval to participate in the study by the treating physician, and - Being aged in the age range 18 years through 65 years

Exclusion criteria

Exclusion criteria: Cardiovascular or other contra-indications (e.g. rheumatic disease) for participating in a physical exercise program. Decisions to exclude potential participants will be made based on the results of the Physical Activities Readiness Questionnaire (PAR-Q) and after consultation with the physician.

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study is self-perceived physical functioning (subscale of SF-36 questionnaire).

Secondary

MeasureTime frame
Global perceived recovery (7-points Likert-scale), tiredness (CIS-20 questionnaire), Quality of life (SF-36 questionnaire), incidence of oral and lung infections (patient files), length of hospital stay, V02 max (submaximal bicycle test), muscle strength of large muscle groups (dynamometer), and lymphocyte count.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)