asthma bronchitis
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Group 1: - Outpatients with non-atopic asthma, determined by negative alatop - Age * 18 yrs - Pulmonologist*s diagnosis of asthma - Documented reversibility in FEV1 of > 12% predicted OR airway hyperresponsiveness to inhaled methacholine Group 2: - Outpatients with atopic asthma, determined by known positive alatop or skin prick test - Age * 18 yrs - Pulmonologist*s diagnosis of asthma - Documented reversibility in FEV1 of > 12% predicted OR airway hyperresponsiveness to inhaled methacholine Group 3: - Subjects without pulmonary history or pulmonary complaints - Age * 18 yrs - No signs of allergy and negative alatop - Normal spirometry
Exclusion criteria
Exclusion criteria: Group 1: - Patients with smoking history of > 10 packyears and persistent airflow obstruction (post bronchodilator FEV1 10 packyears and persistent airflow obstruction (post bronchodilator FEV1
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference between vitamin D levels of patients with non-atopic asthma and and patients with atopic asthma and the difference between vitamin D levels of patients with non-atopic asthmaand healthy non-atopic subjects . | — |
Secondary
| Measure | Time frame |
|---|---|
| virus serology Genetic tests Pulmonary function testing: spirometry ACQ (asthmatic patients) Medical consumption (asthmatic patients) Time spent outdoors | — |
Countries
Netherlands