mild hypercholesterolemia slightly elevated cholesterol
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy male and female subjects, aged 18-65 years, with an LDL-cholesterol concentration between 3.0 and 5.0 mmol/l, who participated in the Dahlia-2a study and who do not use any cholesterol-lowering medication.
Exclusion criteria
Exclusion criteria: Excluded are persons with a genetic hyperlipoproteinemia like familial hypercholesterolemia, LPL-deficiency, familial dysbeta lipoproteinemia and familial hypertriglyceridemia. Also people with diabetes mellitus, severe hypertriglyceridemia, uncontrolled hypertension or history of arterial disease including unstable angina, myocardial infarction, recent transient ischaemic attacks or a cerebro-vascular accidents, will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference in plasma D7-cholesterol enrichment at T=72h, after three different ways of oral D7-cholesterol administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| n.a. | — |
Countries
Netherlands
Outcome results
None listed