HIV-1
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria - Confirmed HIV positive - On ART (regardless of viral load) - Age > 18 - Expected to remain under care at the clinic for as long as the participate in the study ;Has a partner not known to be HIV infected and the following criteria are met: - The partners have had unprotected penetrative anal or vaginal intercourse together in the past month (during which period the HIV negative partner was aware of the HIV status of the HIV positive partner) - The partners expect to have sex together again in the coming months - Both partners consent to attend clinic to complete a risk behaviour questionnaire every 3-6 months for as long as they participate in the study. - The HIV negative partner consents to testing for HIV at these visits. - Both partners consent to provide a separate blood sample if the HIV negative partner should become infected with HIV (this is for an anonymous comparison of viruses * results will not be linked to the partnership)
Exclusion criteria
Exclusion criteria: Pregnancy. (Only upon inclusion, if a woman (whether the negative or the positive partner) becomes pregnant during the study, then the partnership can continue in the study, if they wish to do so).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary analysis will be estimation of the rate of infection in partners per person year of unprotected sex partnership where the index patient has viral load | — |
Secondary
| Measure | Time frame |
|---|---|
| In secondary analyses we will also estimate (i) the rate of infection in partners per unprotected sex act where index patient has viral load | — |
Countries
Netherlands
Outcome results
None listed