chirurgische ASA class I and II patienten die gehele narcose ondergaan closed loop control computer program
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age > 18 years and
Exclusion criteria
Exclusion criteria: patient refusal ASA class > 2 BMI 29 allergy to one of the study medication chronic pain neurological disorder including CVA, stroke, etc* recent use of psycho-active medication, including alcohol abuse history of difficult airway management documented liver and kidney disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to compare the robustness of two existing closed-loop control technologies for BIS-guided propofol administration in combination with open-loop effect-compartment controlled remifentanil infusion. Robustness of the controllers will be evaluated and compared according to widely accepted laboratory performance criteria and peri-operative clinical outcome. | — |
Secondary
| Measure | Time frame |
|---|---|
| In the Bayesian controller, the time course of the Ce50 of propofol versus the CeRemi will be analyzed. In both controllers, hemodynamic stability during induction, maintenance and recovery will be compared between controller groups. Recovery times will be compared between groups. | — |
Countries
Netherlands
Outcome results
None listed