Validation of athe conchotome percutaneous technique to perform a muscle biopsy to measure biochemical parameters in mitochondrial disease

Validation of athe conchotome percutaneous technique to perform a muscle biopsy to measure biochemical parameters in mitochondrial disease - Validation of the conchotome percutaneous muscle biopsy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON34211

Enrollment

Registered

2011-01-06

Start date

2011-03-22

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

energy metabolism disturbance mitopathy

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: - Age 0 - 18 years - Approximately symmetrical use of both legs

Exclusion criteria

Exclusion criteria: - Age > 18 years - Assymatrical use of one leg, for example hemiparesis

Design outcomes

Primary

Measure	Time frame
Primary outcome parameter ATP production in muscle	—

Secondary

Measure	Time frame
Substrate oxidation rates in muscle cells Enzyme complex activities in muscle cells Complications of muscle biopsy	—

Countries

Netherlands

Outcome results