food allergy food hypersensitivity
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Adults (from 18 years) with a (suspicion of) legume (peanut, soy), nut (hazel nut, pecan nut, cashew nut, walnut), cow's milk, fish, egg, shrimp or latex allergy
Exclusion criteria
Exclusion criteria: congenital/acquired immunodeficiency lymphoproliferative disease systemic immunosuppression Only when patients will undergo a food challenge: instabile asthma contra-indication for treatment with epinephrine (instabile angina pectoris, poor controlled hypertension or arrhythmia) use of β-blocker or ACE inhibitor pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To develop a model to predict (the severity of) a food allergy. | — |
Secondary
| Measure | Time frame |
|---|---|
| -New biomarker(s) that can predict (the severity of) a food allergy -To compare sensitivity, specificity and positive and negative predictive value for different diagnostic tests: allergen chip, CAP, skin prick tests, basophil activation test (BAT) and T cell activity -Eliciting doses in walnut allergic patients | — |
Countries
Netherlands
Outcome results
None listed