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Dissociating the role of the inferior frontal gyrus and middle temporal gyrus in language comprehension with transcranial magnetic stimulation

Dissociating the role of the inferior frontal gyrus and middle temporal gyrus in language comprehension with transcranial magnetic stimulation - Dissociating the IFG and MTG in language comprehension with TMS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON34139
Enrollment
20
Registered
2011-01-06
Start date
2011-02-15
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

niet van toepassing not applicable

Interventions

Each participant will receive two different theta-burst stimulations of 600 pulses at 80% of active motor threshold for 40 seconds. Each session will involve one TMS intervention. 1. Continuous TBS

Sponsors

Radboud Universiteit Nijmegen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy, right-handed males and females, aged 18-35 years. All subjects will have normal or corrected-to-normal vision.

Exclusion criteria

Exclusion criteria: Contra-indications for TMS and fMRI: drug abuse, head trauma, neurological or psychiatric illness, pregnancy, heart disease, claustrophobia, cardiac pacemakers, metal objects in the body, medication pumps, tricyclicantidepressants, neuroleptics and a family history of neurological illness, psychiatric illness or epilepsy.

Design outcomes

Primary

MeasureTime frame
Eye movements (fixation durations, forward and backwards saccades, etc) and comprehension accuracy will be measured during the sentence processing task to determine at what stages of sentence processing (i.e., lexical retrieval vs. sentence integration) TMS is having it's effect.

Secondary

MeasureTime frame
No secondary parameters/outcomes

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)