bloeding, opbrengst en kwaliteit van thrombocytentransfusie bleeding transfusion
Conditions
Interventions
None listed
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: thrombopenia (
Exclusion criteria
Exclusion criteria: infection and sepsis, active bleeding, splenomegaly. Treatment with anticoagulants (LMWH,acetylic acid, coumarines) thrombocyte transfusion shorter than 72 hours ago
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Incidence of spontaneous bleeding irrespective TC transfusion. | — |
Primary
| Measure | Time frame |
|---|---|
| Increment of transfuion after 1 and 24 hours (measured by number of thrombocytes and corrected ammount increment-CCI) Differences of Mean platelet volume (MPV) Whole blood impedance measurement (activated by ADP/TRAP/COLL/ASPI) CD62 Microparticles PFA-100 Thrombelastography (for fibrinolysis) | — |
Countries
Netherlands
Outcome results
None listed